Department of Neurosciences "Rita Levi Montalcini"

Research products

All my research products

Selected research products

Boggio Bozzo S, Dell'Oca M, Vaglietti S, Gurgone A, Cardinale V, Ragazzini G, Alessandrini A, Colnaghi L, Bazan JF, Ghirardi M, Giustetto M, Fiumara F. (2026) The CDKL5 kinase undergoes liquid-liquid phase separation driven by a serine-rich C-terminal region. Life science alliance 9(5) [DOI  PMID]

Gurgone A, Cardinale V, Tangari MM, Budicin S, Comai D, Ledda C, Lopiano L, Camussi G, Zibetti M, Giustetto M. (2026) Clinical Validation of alpha-Synuclein in Salivary Extracellular Vesicles as a Biomarker for Parkinson's Disease: A Longitudinal Study. European journal of neurology 33(2) e70508 [DOI  PMID]

Bonato M, Montarolo F, Parolisi R, Caudana M, Abbadessa G, Cardinale V, Nato G, Pandino C, Di Cintio N, Schiavo V, Giustetto M, Luzzati F, De Francia S, Bertolotto A, Buffo A, Boda E. (2025) Acute Particulate Matter (PM(10)) Exposure Selectively Triggers Behavioral Alterations in the Presymptomatic Experimental Autoimmune Encephalomyelitis (EAE) Mouse Model of Multiple Sclerosis. The European journal of neuroscience 62(10) e70304 [DOI  PMID]

Foglietta F, Fragassi A, Pesce C, Arratia FAS, Mangia A, Giustetto M, Durando G, Morano GM, Caliceti P, Grandoni A, Canaparo R, Serpe L, Salmaso S. (2025) Bespoke doxorubicin-loaded gold nanoparticles for ultrasound-guided cancer cell killing. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 193 118777 [DOI  PMID]

Morellato A, De Gregorio M, Angelini C, Torelli F, Belmonte V, Alfieri A, Bersia B, Cravero T, Gai M, Bianciotto OT, Oddone R, Salemme V, Natalini D, Centonze G, Nigrelli F, Raspanti A, Gurgone A, D'Attanasio G, Mele P, Eva C, Lodi A, Gavello D, Carabelli V, Hidisoglu E, Chiantia G, Carbone E, Becchetti A, Giustetto M, Marcantoni A, Turco E, Bertocchi I, Defilippi P. (2025) The adaptor protein SKT interacts with PSD-95 and SHANK3 and affects synaptic functions. Cell reports 44(9) 116206 [DOI  PMID]

Quadalti C, Sannia M, Humphreys NE, Baldassarro VA, Gurgone A, Ascolani M, Zanella L, Giardino L, Gross CT, Croci S, Meloni I, Giustetto M, Renieri A, Lorenzini L, Calza L. (2024) A new knockin mouse carrying the E364X patient mutation for CDKL5 deficiency disorder: neurological, behavioral and molecular profiling. Heliyon 10(21) e40165 [DOI  PMID]

Chiantia G, Comai D, Hidisoglu E, Gurgone A, Franchino C, Carabelli V, Marcantoni A, Giustetto M. (2025) Glyphosate impairs both structure and function of GABAergic synapses in hippocampal neurons. Neuropharmacology 262 110183 [DOI  PMID]

Ait Bali Y, Madougou FA, Ba-M'hamed S, Giustetto M, Bennis M. (2024) Glyphosate-based herbicide exposure affects cognitive flexibility and social cognition in adult mice. Neuroscience letters 837 137912 [DOI  PMID]

Chiantia G, Comai D, Hidisoglu E, Gurgone A, Franchino C, Carabelli V, Marcantoni A, Giustetto M. (2025) Glyphosate impairs both structure and function of GABAergic synapses in hippocampal neurons. Neuropharmacology 262 110183 [DOI  PMID]

Sebastiano MR, Hadano S, Cesca F, Ermondi G. (2024) Preclinical alternative drug discovery programs for monogenic rare diseases. Should small molecules or gene therapy be used? The case of hereditary spastic paraplegias. Drug discovery today 29(10) 104138 [DOI  PMID]

Ait Bali Y, Madougou FA, Ba-M'hamed S, Giustetto M, Bennis M. (2024) Glyphosate-based herbicide exposure affects cognitive flexibility and social cognition in adult mice. Neuroscience letters 837 137912 [DOI  PMID]

Concina G, Gurgone A, Boggio EM, Raspanti A, Pizzo R, Morello N, Castroflorio E, Pizzorusso T, Sacchetti B, Giustetto M. (2023) Stabilizing Immature Dendritic Spines in the Auditory Cortex: A Key Mechanism for mTORC1-Mediated Enhancement of Long-Term Fear Memories. The Journal of neuroscience : the official journal of the Society for Neuroscience 43(50) 8744-8755 [DOI  PMID]

Indrigo M, Morella I, Orellana D, d'Isa R, Papale A, Parra R, Gurgone A, Lecca D, Cavaccini A, Tigaret CM, Cagnotto A, Jones K, Brooks S, Ratto GM, Allen ND, Lelos MJ, Middei S, Giustetto M, Carta AR, Tonini R, Salmona M, Hall J, Thomas K, Brambilla R, Fasano S. (2023) Nuclear ERK1/2 signaling potentiation enhances neuroprotection and cognition via Importinalpha1/KPNA2. EMBO molecular medicine 15(11) e15984 [DOI  PMID]

Pavinato L, Stanic J, Barzasi M, Gurgone A, Chiantia G, Cipriani V, Eberini I, Palazzolo L, Di Luca M, Costa A, Marcantoni A, Biamino E, Spada M, Hiatt SM, Kelley WV, Vestito L, Sisodiya SM, Efthymiou S, Chand P, Kaiyrzhanov R, Bruselles A, Cardaropoli S, Tartaglia M, De Rubeis S, Buxbaum JD, Smedley D, Ferrero GB, Giustetto M, Gardoni F, Brusco A. (2023) Missense variants in RPH3A cause defects in excitatory synaptic function and are associated with a clinically variable neurodevelopmental disorder. Genetics in medicine : official journal of the American College of Medical Genetics 25(11) 100922 [DOI  PMID]

Liaci C, Camera M, Zamboni V, Saro G, Ammoni A, Parmigiani E, Ponzoni L, Hidisoglu E, Chiantia G, Marcantoni A, Giustetto M, Tomagra G, Carabelli V, Torelli F, Sala M, Yanagawa Y, Obata K, Hirsch E, Merlo GR. (2022) Loss of ARHGAP15 affects the directional control of migrating interneurons in the embryonic cortex and increases susceptibility to epilepsy. Frontiers in cell and developmental biology 10 875468 [DOI  PMID]

Hidisoglu E, Chiantia G, Franchino C, Tomagra G, Giustetto M, Carbone E, Carabelli V, Marcantoni A. (2022) The ryanodine receptor-calstabin interaction stabilizer S107 protects hippocampal neurons from GABAergic synaptic alterations induced by Abeta42 oligomers. The Journal of physiology 600(24) 5295-5309 [DOI  PMID]

Medici G, Tassinari M, Galvani G, Bastianini S, Gennaccaro L, Loi M, Mottolese N, Alvente S, Berteotti C, Sagona G, Lupori L, Candini G, Baggett HR, Zoccoli G, Giustetto M, Muotri A, Pizzorusso T, Nakai H, Trazzi S, Ciani E. (2022) Expression of a Secretable, Cell-Penetrating CDKL5 Protein Enhances the Efficacy of Gene Therapy for CDKL5 Deficiency Disorder. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 19(6) 1886-1904 [DOI  PMID]

Angelini C, Morellato A, Alfieri A, Pavinato L, Cravero T, Bianciotto OT, Salemme V, Natalini D, Centonze G, Raspanti A, Garofalo T, Valdembri D, Serini G, Marcantoni A, Becchetti A, Giustetto M, Turco E, Defilippi P. (2022) p140Cap Regulates the Composition and Localization of the NMDAR Complex in Synaptic Lipid Rafts. The Journal of neuroscience : the official journal of the Society for Neuroscience 42(38) 7183-7200 [DOI  PMID]

Gurgone A, Pizzo R, Raspanti A, Chiantia G, Devi S, Comai D, Morello N, Pilotto F, Gnavi S, Lupori L, Mazziotti R, Sagona G, Putignano E, Nocentini A, Supuran CT, Marcantoni A, Pizzorusso T, Giustetto M. (2023) mGluR5 PAMs rescue cortical and behavioural defects in a mouse model of CDKL5 deficiency disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 48(6) 877-886 [DOI  PMID]

Ait Bali Y, Kaikai NE, Ba-M'hamed S, Sassoe-Pognetto M, Giustetto M, Bennis M. (2022) Anxiety and Gene Expression Enhancement in Mice Exposed to Glyphosate-Based Herbicide. Toxics 10(5) [DOI  PMID]

Gennaccaro L, Fuchs C, Loi M, Pizzo R, Alvente S, Berteotti C, Lupori L, Sagona G, Galvani G, Gurgone A, Raspanti A, Medici G, Tassinari M, Trazzi S, Ren E, Rimondini R, Pizzorusso T, Giovanna Z, Maurizio G, Elisabetta C. (2021) Age-Related Cognitive and Motor Decline in a Mouse Model of CDKL5 Deficiency Disorder is Associated with Increased Neuronal Senescence and Death. Aging and disease 12(3) 764-785 [DOI  PMID]

Gennaccaro L, Fuchs C, Loi M, Roncace V, Trazzi S, Ait-Bali Y, Galvani G, Berardi AC, Medici G, Tassinari M, Ren E, Rimondini R, Giustetto M, Aicardi G, Ciani E. (2021) A GABAB receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder. Neurobiology of disease 153 105304 [DOI  PMID]

Carli S, Chaabane L, Butti C, De Palma C, Aimar P, Salio C, Vignoli A, Giustetto M, Landsberger N, Frasca A. (2021) In vivo magnetic resonance spectroscopy in the brain of Cdkl5 null mice reveals a metabolic profile indicative of mitochondrial dysfunctions. Journal of neurochemistry 157(4) 1253-1269 [DOI  PMID]

Marcantoni A, Cerullo MS, Buxeda P, Tomagra G, Giustetto M, Chiantia G, Carabelli V, Carbone E. (2020) Amyloid Beta42 oligomers up-regulate the excitatory synapses by potentiating presynaptic release while impairing postsynaptic NMDA receptors. The Journal of physiology 598(11) 2183-2197 [DOI  PMID]

Ait-Bali Y, Ba-M'hamed S, Gambarotta G, Sassoe-Pognetto M, Giustetto M, Bennis M. (2020) Pre- and postnatal exposure to glyphosate-based herbicide causes behavioral and cognitive impairments in adult mice: evidence of cortical ad hippocampal dysfunction. Archives of toxicology 94(5) 1703-1723 [DOI  PMID]

Gioelli N, Maione F, Camillo C, Ghitti M, Valdembri D, Morello N, Darche M, Zentilin L, Cagnoni G, Qiu Y, Giacca M, Giustetto M, Paques M, Cascone I, Musco G, Tamagnone L, Giraudo E, Serini G. (2018) A rationally designed NRP1-independent superagonist SEMA3A mutant is an effective anticancer agent. Science translational medicine 10(442) [DOI  PMID]

Russo I, Gavello D, Menna E, Vandael D, Veglia C, Morello N, Corradini I, Focchi E, Alfieri A, Angelini C, Bianchi FT, Morellato A, Marcantoni A, Sassoe-Pognetto M, Ottaviani MM, Yekhlef L, Giustetto M, Taverna S, Carabelli V, Matteoli M, Carbone E, Turco E, Defilippi P. (2019) p140Cap Regulates GABAergic Synaptogenesis and Development of Hippocampal Inhibitory Circuits. Cerebral cortex (New York, N.Y. : 1991) 29(1) 91-105 [DOI  PMID]

Vicidomini C, Ponzoni L, Lim D, Schmeisser MJ, Reim D, Morello N, Orellana D, Tozzi A, Durante V, Scalmani P, Mantegazza M, Genazzani AA, Giustetto M, Sala M, Calabresi P, Boeckers TM, Sala C, Verpelli C. (2017) Homer1b/c clustering is impaired in Phelan-McDermid Syndrome iPSCs derived neurons. Molecular psychiatry 22(5) 637 [DOI  PMID]

Morello N, Plicato O, Piludu MA, Poddighe L, Serra MP, Quartu M, Corda MG, Giorgi O, Giustetto M. (2017) Effects of Forced Swimming Stress on ERK and Histone H3 Phosphorylation in Limbic Areas of Roman High- and Low-Avoidance Rats. PloS one 12(1) e0170093 [DOI  PMID]

Pizzo R, Gurgone A, Castroflorio E, Amendola E, Gross C, Sassoe-Pognetto M, Giustetto M. (2016) Lack of Cdkl5 Disrupts the Organization of Excitatory and Inhibitory Synapses and Parvalbumin Interneurons in the Primary Visual Cortex. Frontiers in cellular neuroscience 10 261 [DOI  PMID]

Meziane H, Khelfaoui M, Morello N, Hiba B, Calcagno E, Reibel-Foisset S, Selloum M, Chelly J, Humeau Y, Riet F, Zanni G, Herault Y, Bienvenu T, Giustetto M, Billuart P. (2016) Fasudil treatment in adult reverses behavioural changes and brain ventricular enlargement in Oligophrenin-1 mouse model of intellectual disability. Human molecular genetics 25(11) 2314-2323 [DOI  PMID]

Vicidomini C, Ponzoni L, Lim D, Schmeisser MJ, Reim D, Morello N, Orellana D, Tozzi A, Durante V, Scalmani P, Mantegazza M, Genazzani AA, Giustetto M, Sala M, Calabresi P, Boeckers TM, Sala C, Verpelli C. (2017) Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice. Molecular psychiatry 22(5) 784 [DOI  PMID]

Vicidomini C, Ponzoni L, Lim D, Schmeisser MJ, Reim D, Morello N, Orellana D, Tozzi A, Durante V, Scalmani P, Mantegazza M, Genazzani AA, Giustetto M, Sala M, Calabresi P, Boeckers TM, Sala C, Verpelli C. (2017) Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice. Molecular psychiatry 22(5) 689-702 [DOI  PMID]

Della Sala G, Putignano E, Chelini G, Melani R, Calcagno E, Michele Ratto G, Amendola E, Gross CT, Giustetto M, Pizzorusso T. (2016) Dendritic Spine Instability in a Mouse Model of CDKL5 Disorder Is Rescued by Insulin-like Growth Factor 1. Biological psychiatry 80(4) 302-311 [DOI  PMID]

Tomassy GS, Morello N, Calcagno E, Giustetto M. (2014) Developmental abnormalities of cortical interneurons precede symptoms onset in a mouse model of Rett syndrome. Journal of neurochemistry 131(1) 115-27 [DOI  PMID]

Amendola E, Zhan Y, Mattucci C, Castroflorio E, Calcagno E, Fuchs C, Lonetti G, Silingardi D, Vyssotski AL, Farley D, Ciani E, Pizzorusso T, Giustetto M, Gross CT. (2014) Mapping pathological phenotypes in a mouse model of CDKL5 disorder. PloS one 9(5) e91613 [DOI  PMID]

Ciccarelli A, Giustetto M. (2014) Role of ERK signaling in activity-dependent modifications of histone proteins. Neuropharmacology 80 34-44 [DOI  PMID]

Repetto D, Camera P, Melani R, Morello N, Russo I, Calcagno E, Tomasoni R, Bianchi F, Berto G, Giustetto M, Berardi N, Pizzorusso T, Matteoli M, Di Stefano P, Missler M, Turco E, Di Cunto F, Defilippi P. (2014) p140Cap regulates memory and synaptic plasticity through Src-mediated and citron-N-mediated actin reorganization. The Journal of neuroscience : the official journal of the Society for Neuroscience 34(4) 1542-53 [DOI  PMID]

Arroyo AI, Camoletto PG, Morando L, Sassoe-Pognetto M, Giustetto M, Van Veldhoven PP, Schuchman EH, Ledesma MD. (2014) Pharmacological reversion of sphingomyelin-induced dendritic spine anomalies in a Niemann Pick disease type A mouse model. EMBO molecular medicine 6(3) 398-413 [DOI  PMID]

Marcello E, Saraceno C, Musardo S, Vara H, de la Fuente AG, Pelucchi S, Di Marino D, Borroni B, Tramontano A, Perez-Otano I, Padovani A, Giustetto M, Gardoni F, Di Luca M. (2013) Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer's disease. The Journal of clinical investigation 123(6) 2523-38 [DOI  PMID]

Ciccarelli A, Calza A, Santoru F, Grasso F, Concas A, Sassoe-Pognetto M, Giustetto M. (2013) Morphine withdrawal produces ERK-dependent and ERK-independent epigenetic marks in neurons of the nucleus accumbens and lateral septum. Neuropharmacology 70 168-79 [DOI  PMID]

Katz DM, Berger-Sweeney JE, Eubanks JH, Justice MJ, Neul JL, Pozzo-Miller L, Blue ME, Christian D, Crawley JN, Giustetto M, Guy J, Howell CJ, Kron M, Nelson SB, Samaco RC, Schaevitz LR, St Hillaire-Clarke C, Young JL, Zoghbi HY, Mamounas LA. (2012) Preclinical research in Rett syndrome: setting the foundation for translational success. Disease models & mechanisms 5(6) 733-45 [DOI  PMID]

Ciccarelli A, Calza A, Panzanelli P, Concas A, Giustetto M, Sassoe-Pognetto M. (2012) Organization of GABAergic synaptic circuits in the rat ventral tegmental area. PloS one 7(10) e46250 [DOI  PMID]

Chapleau CA, Boggio EM, Calfa G, Percy AK, Giustetto M, Pozzo-Miller L. (2012) Hippocampal CA1 pyramidal neurons of Mecp2 mutant mice show a dendritic spine phenotype only in the presymptomatic stage. Neural plasticity 2012 976164 [DOI  PMID]

Landi S, Putignano E, Boggio EM, Giustetto M, Pizzorusso T, Ratto GM. (2011) The short-time structural plasticity of dendritic spines is altered in a model of Rett syndrome. Scientific reports 1 45 [DOI  PMID]

Lopez-Atalaya JP, Ciccarelli A, Viosca J, Valor LM, Jimenez-Minchan M, Canals S, Giustetto M, Barco A. (2011) CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement. The EMBO journal 30(20) 4287-98 [DOI  PMID]

Paolicelli RC, Bolasco G, Pagani F, Maggi L, Scianni M, Panzanelli P, Giustetto M, Ferreira TA, Guiducci E, Dumas L, Ragozzino D, Gross CT. (2011) Synaptic pruning by microglia is necessary for normal brain development. Science (New York, N.Y.) 333(6048) 1456-8 [DOI  PMID]

Ricciardi S, Boggio EM, Grosso S, Lonetti G, Forlani G, Stefanelli G, Calcagno E, Morello N, Landsberger N, Biffo S, Pizzorusso T, Giustetto M, Broccoli V. (2011) Reduced AKT/mTOR signaling and protein synthesis dysregulation in a Rett syndrome animal model. Human molecular genetics 20(6) 1182-96 [DOI  PMID]

Epis R, Marcello E, Gardoni F, Vastagh C, Malinverno M, Balducci C, Colombo A, Borroni B, Vara H, Dell'Agli M, Cattabeni F, Giustetto M, Borsello T, Forloni G, Padovani A, Di Luca M. (2010) Blocking ADAM10 synaptic trafficking generates a model of sporadic Alzheimer's disease. Brain : a journal of neurology 133(11) 3323-35 [DOI  PMID]

Pavlowsky A, Zanchi A, Pallotto M, Giustetto M, Chelly J, Sala C, Billuart P. (2010) Neuronal JNK pathway activation by IL-1 is mediated through IL1RAPL1, a protein required for development of cognitive functions. Communicative & integrative biology 3(3) 245-7 [DOI  PMID]

Rust MB, Gurniak CB, Renner M, Vara H, Morando L, Gorlich A, Sassoe-Pognetto M, Banchaabouchi MA, Giustetto M, Triller A, Choquet D, Witke W. (2010) Learning, AMPA receptor mobility and synaptic plasticity depend on n-cofilin-mediated actin dynamics. The EMBO journal 29(11) 1889-902 [DOI  PMID]

Lonetti G, Angelucci A, Morando L, Boggio EM, Giustetto M, Pizzorusso T. (2010) Early environmental enrichment moderates the behavioral and synaptic phenotype of MeCP2 null mice. Biological psychiatry 67(7) 657-65 [DOI  PMID]

Pavlowsky A, Gianfelice A, Pallotto M, Zanchi A, Vara H, Khelfaoui M, Valnegri P, Rezai X, Bassani S, Brambilla D, Kumpost J, Blahos J, Roux MJ, Humeau Y, Chelly J, Passafaro M, Giustetto M, Billuart P, Sala C. (2010) A postsynaptic signaling pathway that may account for the cognitive defect due to IL1RAPL1 mutation. Current biology : CB 20(2) 103-15 [DOI  PMID]

Boggio EM, Lonetti G, Pizzorusso T, Giustetto M. (2010) Synaptic determinants of rett syndrome. Frontiers in synaptic neuroscience 2 28 [DOI  PMID]

Vara H, Onofri F, Benfenati F, Sassoe-Pognetto M, Giustetto M. (2009) ERK activation in axonal varicosities modulates presynaptic plasticity in the CA3 region of the hippocampus through synapsin I. Proceedings of the National Academy of Sciences of the United States of America 106(24) 9872-7 [DOI  PMID]

Fasano S, D'Antoni A, Orban PC, Valjent E, Putignano E, Vara H, Pizzorusso T, Giustetto M, Yoon B, Soloway P, Maldonado R, Caboche J, Brambilla R. (2009) Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) controls activation of extracellular signal-regulated kinase (ERK) signaling in the striatum and long-term behavioral responses to cocaine. Biological psychiatry 66(8) 758-68 [DOI  PMID]

Camoletto PG, Vara H, Morando L, Connell E, Marletto FP, Giustetto M, Sassoe-Pognetto M, Van Veldhoven PP, Ledesma MD. (2009) Synaptic vesicle docking: sphingosine regulates syntaxin1 interaction with Munc18. PloS one 4(4) e5310 [DOI  PMID]

Boggio EM, Putignano E, Sassoe-Pognetto M, Pizzorusso T, Giustetto M. (2007) Visual stimulation activates ERK in synaptic and somatic compartments of rat cortical neurons with parallel kinetics. PloS one 2(7) e604 [DOI  PMID]

Pilo Boyl P, Di Nardo A, Mulle C, Sassoe-Pognetto M, Panzanelli P, Mele A, Kneussel M, Costantini V, Perlas E, Massimi M, Vara H, Giustetto M, Witke W. (2007) Profilin2 contributes to synaptic vesicle exocytosis, neuronal excitability, and novelty-seeking behavior. The EMBO journal 26(12) 2991-3002 [DOI  PMID]

Si K, Giustetto M, Etkin A, Hsu R, Janisiewicz AM, Miniaci MC, Kim JH, Zhu H, Kandel ER. (2003) A neuronal isoform of CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia. Cell 115(7) 893-904 [DOI  PMID]

Giustetto M, Hegde AN, Si K, Casadio A, Inokuchi K, Pei W, Kandel ER, Schwartz JH. (2003) Axonal transport of eukaryotic translation elongation factor 1alpha mRNA couples transcription in the nucleus to long-term facilitation at the synapse. Proceedings of the National Academy of Sciences of the United States of America 100(23) 13680-5 [DOI  PMID]

Guan Z, Giustetto M, Lomvardas S, Kim JH, Miniaci MC, Schwartz JH, Thanos D, Kandel ER. (2002) Integration of long-term-memory-related synaptic plasticity involves bidirectional regulation of gene expression and chromatin structure. Cell 111(4) 483-93 [DOI  PMID]

Bailey CH, Giustetto M, Huang YY, Hawkins RD, Kandel ER. (2000) Is heterosynaptic modulation essential for stabilizing Hebbian plasticity and memory? Nature reviews. Neuroscience 1(1) 11-20 [DOI  PMID]

Bartsch D, Ghirardi M, Casadio A, Giustetto M, Karl KA, Zhu H, Kandel ER. (2000) Enhancement of memory-related long-term facilitation by ApAF, a novel transcription factor that acts downstream from both CREB1 and CREB2. Cell 103(4) 595-608 [DOI  PMID]

Bailey CH, Giustetto M, Zhu H, Chen M, Kandel ER. (2000) A novel function for serotonin-mediated short-term facilitation in aplysia: conversion of a transient, cell-wide homosynaptic hebbian plasticity into a persistent, protein synthesis-independent synapse-specific enhancement. Proceedings of the National Academy of Sciences of the United States of America 97(21) 11581-6 [DOI  PMID]

Casadio A, Martin KC, Giustetto M, Zhu H, Chen M, Bartsch D, Bailey CH, Kandel ER. (1999) A transient, neuron-wide form of CREB-mediated long-term facilitation can be stabilized at specific synapses by local protein synthesis. Cell 99(2) 221-37 [DOI  PMID]

Sassoe-Pognetto M, Giustetto M, Panzanelli P, Cantino D, Kirsch J, Fritschy JM. (1999) Postsynaptic colocalization of gephyrin and GABAA receptors. Annals of the New York Academy of Sciences 868 693-6 [DOI  PMID]

Quaglino E, Giustetto M, Panzanelli P, Cantino D, Fasolo A, Sassoe-Pognetto M. (1999) Immunocytochemical localization of glutamate and gamma-aminobutyric acid in the accessory olfactory bulb of the rat. The Journal of comparative neurology 408(1) 61-72 [DOI  PMID]

Giustetto M, Kirsch J, Fritschy JM, Cantino D, Sassoe-Pognetto M. (1998) Localization of the clustering protein gephyrin at GABAergic synapses in the main olfactory bulb of the rat. The Journal of comparative neurology 395(2) 231-44 [DOI  PMID]

Giustetto M, Bovolin P, Fasolo A, Bonino M, Cantino D, Sassoe-Pognetto M. (1997) Glutamate receptors in the olfactory bulb synaptic circuitry: heterogeneity and synaptic localization of N-methyl-D-aspartate receptor subunit 1 and AMPA receptor subunit 1. Neuroscience 76(3) 787-98 [DOI  PMID]

Sassoe-Pognetto M, Cantino D, Panzanelli P, Verdun di Cantogno L, Giustetto M, Margolis FL, De Biasi S, Fasolo A. (1993) Presynaptic co-localization of carnosine and glutamate in olfactory neurones. Neuroreport 5(1) 7-10 [DOI  PMID]

Courses

• Anatomia (MED3033A)
  Corso di laurea in Infermieristica - Aosta
• Anatomia umana II (canale A) (SME0718)
  Laurea Magistrale in Medicina e Chirurgia - sede di Torino
• STRUTTURA E MORFOLOGIA DEL CORPO UMANO (MED3033)
  Corso di laurea in Infermieristica - Aosta
• TIROCINIO di CIRCUITI E SINAPSI NELLE PATOLOGIE DELLO SPETTRO AUTISTICO (SME0975)
  Corso di Laurea Magistrale in Biotecnologie Mediche - Classe LM-9

Research topics

Mi occupo della plasticità neuronale alla base di processi cognitivi e delle sua alterazioni patologiche causa di ritardo mentale.

Nel laboratorio studiamo da oltre 15 anni le basi neurobiologiche della sindrome di Rett e della Malattia CDKL5, due gravissimi disordini neurologici dello sviluppo che colpiscono nella maggior parte dei casi le bambine.

Per maggiori informazioni sulle patologie studiate:

https://www.osservatoriomalattierare.it/malattie-rare/epilessia/16177-sindrome-cdkl5-la-terapia-si-avvicina-grazie-a-scienza-e-associazioni

http://www.lalberodigreta.org/alberodigreta/index.php

http://www.cdkl5insiemeversolacura.it/en/home-page-en/

https://www.cdkl5.com/

https://www.louloufoundation.org/

http://www.rettsyndrome.org/

http://www.rettsyndrome.org/news-and-media/irsf-features/investigator-spotlight#Giustetto

Research groups

• Basi neuronali delle malattie rare del neurosviluppo
• Organizzazione delle sinapsi e sviluppo

Activities in agenda

See my calendar

Academic bodies

• Junta

• Commissione Terza Missione 2021-2024
• Consiglio di Dipartimento

Office hours

Previo appuntamento.

Elenco delle mie pubblicazioni su riviste scientifiche internazionali

http://www.ncbi.nlm.nih.gov/pubmed/?term=giustetto+m

Sito web

https://neuroen.campusnet.unito.it/do/gruppi.pl/Show?_id=38jd

Indirizzo  Webex: 

https://unito.webex.com/meet/maurizio.giustetto