Clinical, neuropsychological and biological links of Mood Disorders, OCD and ADHD

Principal Investigator: Prof. Giuseppe Maina

Group members:

• Giuseppe Maina - Full Professor, Principal Investigator
• Gianluca Rosso - Associate Professor
• Gabriele Di Salvo - RTDA
• Stefano Bramante – PhD Student
• Emina Mehanovic – PhD Student
• Elena Teobaldi- PhD Student
• Caterina Portaluppi - Research Fellow

Address and contacts:

• Giuseppe Maina, tel. 0119026504, giuseppe.maina@unito.it

Main research activities of the research group

The clinical research activity is focused on mood disorders, mainly bipolar disorders and treatment resistant depression, with reference to pharmacological treatment and psychotherapy, biomarkers, perinatal psychiatry and the relationships with obsessive-compulsive disorder (OCD) and attention-deficit/hyperactivity disorder (ADHD).

List of 10 main publications

• Mehanović E, Rosso G, Cuomo GL, Diecidue R, Maina G, Costa G, Vigna-Taglianti F. Cause-specific mortality after hospital discharge for suicide attempt or suicidal ideation: A cohort study in Piedmont Region, Italy. J Psychiatr Res. 2023 Mar 1;161:19-26. doi: 10.1016/j.jpsychires.2023.02.035. Epubahead of print. PMID: 36893667.
• Bramante S, Maina G, Borgogno R, Pellegrini L, Rigardetto S, Albert U. Assessing suicide risk in patients with Obsessive-Compulsive Disorder: a dimensional approach. Braz J Psychiatry. 2022 Sep 12;45(1):28–37. doi:10.47626/1516-4446-2022-2632. Epub ahead of print. PMID: 36099257; PMCID:PMC9976916.
• Parpinel G, Rosso G, Galante A, Germano C, Aragno E, Girlando F, Messina A, Laudani ME, Rolfo A, Attini R, Revelli A, Maina G, Masturzo B. Effect of Depressive Disorders and Their Pharmacological Treatment during Pregnancy on Maternal and Neonatal Outcome. J Clin Med. 2022 Mar 9;11(6):1486. doi:10.3390/jcm11061486. PMID: 35329810; PMCID: PMC8948944.
• Teobaldi E, Albert U, Di Salvo G, Mencacci C, Rosso G, Salvi V, Maina G. Manic-Depressive Cycles in Bipolar Disorder: Clinical and Treatment Implications. Psychopathology. 2021;54(2):98-105. doi: 10.1159/000513314. Epub 2021 Feb 24. PMID: 33626525.
• Di Salvo G, Pessina E, Aragno E, Martini A, Albert U, Maina G, Rosso G. Impact of comorbid obsessive-compulsive disorder on suicidality in patients with bipolar disorder. Psychiatry Res. 2020 Aug;290:113088. doi:10.1016/j.psychres.2020.113088. Epub 2020 May 21. PMID: 32470722.
• Rosso G, Aragno E, Mehanović E, Di Salvo G, Maina G. Age at Menarche in Women With Bipolar Disorder: Correlation With Clinical Features and Peripartum Episodes. Front Psychiatry. 2020 Sep 4;11:00851. doi: 10.3389/fpsyt.2020.00851. PMID: 33033479; PMCID: PMC7509456.
• Rosso G, Albert U, Bramante S, Aragno E, Quarato F, Di Salvo G, Maina G. Correlates of violent suicide attempts in patients with bipolar disorder. Compr Psychiatry. 2020 Jan;96:152136. doi: 10.1016/j.comppsych.2019.152136. Epub 2019 Oct 10. PMID: 31734642.
• Rosso G, Aragno E, Cuomo A, Fagiolini A, Di Salvo G, Maina G. Five-year follow-up of first-episode depression treated with psychodynamic psychotherapy or antidepressants. Psychiatry Res. 2019 May;275:27-30. doi:10.1016/j.psychres.2019.02.073. Epub 2019 Feb 28. PMID: 30878853.
• Albert U, Barbaro F, Bramante S, Rosso G, De Ronchi D, Maina G. Duration of untreated illness and response to SRI treatment in Obsessive-Compulsive Disorder. Eur Psychiatry. 2019 May;58:19-26. doi: 10.1016/j.eurpsy.2019.01.017. Epub 2019 Feb 11. PMID: 30763828.
• Albert U, Marazziti D, Di Salvo G, Solia F, Rosso G, Maina G. A Systematic Review of Evidence-based Treatment Strategies for Obsessive- compulsive Disorder Resistant to first-line Pharmacotherapy. Curr Med Chem. 2018;25(41):5647-5661. doi: 10.2174/0929867325666171222163645. PMID: 29278206.