PICTURE
NOT AVAILABLE

Behavioral Neurophysiology

Physiology

Staff

Sacchetti Benedetto (Coordinator)
(Member)
(Member)
Concina Giulia (Member)
Renna Annamaria (Member)
Sacco Tiziana (Member)
Eugenio Manassero (Member)

Contacts

Send email to members

ERC Sectors

LS5_9 - Neural basis of cognition

Activity

The laboratory is interested in the analysis of neural mechanisms underlying the learning and memory processes, with particular attention to the formation of emotionally salient events memories. This study uses methods of behavioral analysis (classical and operant conditioning, spatial and relational memory test, baseline levels of fear and anxiety analysis), electrophysiological recordings (recordings by the patch-clamp technique, extracellular recordings in vitro, recordings in vivo) and immunohistochemical techniques (analysis of gene expression). The laboratory is part of the National Institute of Neuroscience and collaborates with international laboratories.

Group’s ECR Sectors:

LS5_2 - Molecular and cellular neuroscience

LS5_4 - Sensory systems (e.g. visual system, auditory system)

LS5_7 - Cognition (e.g. learning, memory, emotions, speech)

LS5_8 - Behavioural neuroscience (e.g. sleep, consciousness, handedness)

Publications

Cambiaghi, Marco, Grosso, Anna, Renna, Annamaria, Concina, Giulia, Sacchetti, Benedetto (2015)
Acute administration of nicotine into the higher order auditory Te2 cortex specifically decreases the fear-related charge of remote emotional memories.
https://iris.unito.it/handle/2318/1526410

Cambiaghi, Marco, Sacchetti, Benedetto (2015)
The crosstalk within theta rhythms between secondary auditory cortex and basolateral amygdala is essential during remote fear memory recall.
https://iris.unito.it/handle/2318/1526451

Cambiaghi, Marco, Sacchetti, Benedetto (2015)
Reversal inactivation of Te2 impairs remote fear memory and BLA learned-plasticity.
https://iris.unito.it/handle/2318/1526450

Cambiaghi, Marco, Sacchetti, Benedetto (2015)
Neural circuitry of long-term fear memories.
https://iris.unito.it/handle/2318/1526449

Cambiaghi, Marco, Grosso, Anna, Concina, Giulia, Renna, Annamaria, Sacco, Tiziana, Sacchetti, Benedetto (2015)
The crosstalk within theta rhythms between secondary auditory cortex and basolateral amygdala is essential during fear memory recall.
https://iris.unito.it/handle/2318/1526452

Grosso, Anna, Cambiaghi, Marco, Renna, Annamaria, Milano, Luisella, Merlo, Giorgio Roberto, Sacco, Tiziana, Sacchetti, Benedetto (2015)
Value coding neurons in lateral amygdala are recruited by both unconditioned and learned emotional stimuli.
https://iris.unito.it/handle/2318/1526463

Grosso, Anna, Cambiaghi, Marco, Renna, Annamaria, Milano, Luisella, Merlo, Giorgio Roberto, Sacco, Tiziana, Sacchetti, Benedetto (2015)
The assignment of the affective/motivational value to sensory stimuli is mediated by the Te2 cortex.
https://iris.unito.it/handle/2318/1526461

Auditory cortex involvement in emotional learning and memory. Neuroscience 299 45-55 [DOI PMID]

Cambiaghi M, Sacchetti B. (2015) Ivan Petrovich Pavlov (1849-1936). Journal of neurology 262(6) 1599-600 [DOI PMID]

Strata P, Scelfo B, Sacchetti B. (2011) Involvement of cerebellum in emotional behavior. Physiological research / Academia Scientiarum Bohemoslovaca 60 Suppl 1 S39-48 [PMID]

Ruediger S, Vittori C, Bednarek E, Genoud C, Strata P, Sacchetti B, Caroni P. (2011) Learning-related feedforward inhibitory connectivity growth required for memory precision. Nature 473(7348) 514-8 [DOI PMID]

Zhu L, Sacco T, Strata P, Sacchetti B. (2011) Basolateral amygdala inactivation impairs learning-induced long-term potentiation in the cerebellar cortex. PloS one 6(1) e16673 [DOI PMID]

Sacco T, Sacchetti B. (2010) Role of secondary sensory cortices in emotional memory storage and retrieval in rats. Science (New York, N.Y.) 329(5992) 649-56 [DOI PMID]