Schizophrenia Spectrum Disorders
The research focuses on the study of psychopathology, cognitive functions, social cognition and social functioning in schizophrenia spectrum disorders, the assessment of their possible relations, of their performance during the progress of the disease and the impact on their pharmacological treatment (traditional and new antipsychotics) and rehabilitation.
The group participates to the Italian Network for Research on Psychosis: a multicenter study on factors affecting social functioning in the real life of people with schizophrenia, which is a member of the Steering Committee, and to the integrated Protocol of structural-functional brain imaging . The study aims in assessing the role of factors related to the disease, the person resources and the context, the heritability of the factors related to the disease and the genetic variants associated with them. The imaging protocol aims to investigate the association between social functioning and endo-phenotypes of structural and functional neuroimaging, as the volumetric alteration of cortex, of subcortical grey matter areas and white matter, brain activity during working memory and attention tests, emotional stimuli processing and brain connectivity during rest, using functional magnetic resonance imaging (FMRi). The group is also conducting research on the evaluation of abnormal connectivity and of brain complexity in schizophrenia, using high-resolution EEG.
In the field of clinical psychopharmacology, the research group carries out studies on the effectiveness and safety of new psychotropic drugs in schizophrenia, and acute psychosis, and is involved in several multicenter controlled studies (national and international).
Group’s ECR Sectors:
LS5_10 - Neuroimaging and computational neuroscience
LS5_12 - Psychiatric disorders (e.g. schizophrenia, autism, Tourette’s syndrome, obsessive compulsive disorder, depression, bipolar disorder, attention deficit hyperactivity disorder
LS5_3 - Neurochemistry and neuropharmacology
LS5_7 - Cognition (e.g. learning, memory, emotions, speech)
LS7_2 - Diagnostic tools (e.g. genetic, imaging)
Mucci A, Galderisi S, Merlotti E, Rossi A, Rocca P, Bucci P, Piegari G, Chieffi M, Vignapiano A, Maj M. (2015) The Brief Negative Symptom Scale (BNSS): Independent validation in a large sample of Italian patients with schizophrenia. European psychiatry : the journal of the Association of European Psychiatrists [DOI PMID]
Montemagni C, Castagna F, Crivelli B, De Marzi G, Frieri T, Macri A, Rocca P. (2014) Relative contributions of negative symptoms, insight, and coping strategies to quality of life in stable schizophrenia. Psychiatry research 220(1-2) 102-11 [DOI PMID]
Rocca P, Montemagni C, Zappia S, Pitera R, Sigaudo M, Bogetto F. (2014) Negative symptoms and everyday functioning in schizophrenia: a cross-sectional study in a real world-setting. Psychiatry research 218(3) 284-9 [DOI PMID]
Birindelli N, Montemagni C, Crivelli B, Bava I, Mancini I, Rocca P. (2014) Cognitive functioning and insight in schizophrenia and in schizoaffective disorder. Rivista di psichiatria 49(2) 77-83 [DOI PMID]
Sigaudo M, Crivelli B, Castagna F, Giugiario M, Mingrone C, Montemagni C, Rocca G, Rocca P. (2014) Quality of life in stable schizophrenia: the relative contributions of disorganization and cognitive dysfunction. Schizophrenia research 153(1-3) 196-203 [DOI PMID]
Frieri T, Montemagni C, Rocca G, Rocca P, Villari V. (2013) Clinical outcome and length of stay in an Italian Psychiatric Emergency Service. Social psychiatry and psychiatric epidemiology 48(6) 1013-20 [DOI PMID]
Mingrone C, Rocca P, Castagna F, Montemagni C, Sigaudo M, Scalese M, Rocca G, Bogetto F. (2013) Insight in stable schizophrenia: relations with psychopathology and cognition. Comprehensive psychiatry 54(5) 484-92 [DOI PMID]
Castagna F, Montemagni C, Maria Milani A, Rocca G, Rocca P, Casacchia M, Bogetto F. (2013) Prosody recognition and audiovisual emotion matching in schizophrenia: the contribution of cognition and psychopathology. Psychiatry research 205(3) 192-8 [DOI PMID]
Zappia S, Montemagni C, Macri A, Sandei L, Sigaudo M, Rocca P. (2012) [Coping styles in schizophrenia: study of clinical and functional variables as determinants of strategies to cope with stress]. Rivista di psichiatria 47(3) 238-45 [DOI PMID]
Montemagni C, Frieri T, Villari V, Rocca P. (2012) Compulsory admissions of emergency psychiatric inpatients in Turin: the role of diagnosis. Progress in neuro-psychopharmacology & biological psychiatry 39(2) 288-94 [DOI PMID]
Birindelli N, Castagna F, Giugiario M, Graffino M, Mingrone C, Sandei L, Rocca P. (2012) [Competitive employment in schizophrenia: clinical and neuropsychological correlates and quality of life]. Rivista di psichiatria 47(2) 89-95 [DOI PMID]